Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.7
USERS' SCORE
Good
Based on 3 Reviews
8
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Glutathione (Reduced Form)
500 mg
**
Milk Thistle Extract (Silybum marianum) (Fruit/Seeds) (Standardized to 80 mg Silymarin Flavonoids - equivalent 80%)
100 mg
**
Alpha Lipoic Acid
50 mg
**
Top Medical Research Studies
9
We investigated the effects of 2,3-dehydrosilybin, a component of silybum marianum, on heart protection during ischemia and reperfusion injuries in rats. Hearts treated with low doses of this compound experienced significantly reduced damage compared to untreated ones—only about 7.5% of the heart was affected versus over 75% in controls.
This suggests that silybum marianum could effectively support heart health by minimizing injury during heart attacks. Importantly, when specific kinases were inhibited, this protective effect vanished, highlighting the complexity of the mechanisms involved.
This suggests that silybum marianum could effectively support heart health by minimizing injury during heart attacks. Importantly, when specific kinases were inhibited, this protective effect vanished, highlighting the complexity of the mechanisms involved.
Read More
9
Silybum marianum shows heart protection
We examined how silybum marianum, commonly known as milk thistle, impacts the heart during and after a heart attack in pigs.
In the first phase of our study, animals that received milk thistle before a heart attack showed reduced heart damage compared to those who did not.
In the recovery period, those on a continuous milk thistle diet also displayed better heart remodeling and function.
However, there were no significant benefits observed in pigs without heart attacks.
In the first phase of our study, animals that received milk thistle before a heart attack showed reduced heart damage compared to those who did not.
In the recovery period, those on a continuous milk thistle diet also displayed better heart remodeling and function.
However, there were no significant benefits observed in pigs without heart attacks.
Read More
8
We explored the potential benefits of Silybum marianum (SM) on heart health, specifically looking at its effects on cardiac lipotoxicity after a heart attack in pigs. In our study, pigs received either SM or a placebo for ten days.
The results were promising; those treated with SM showed a significant decrease in plasma triglyceride levels. This reduction was linked to less absorption of triglycerides and improved heart function.
Despite these findings, no significant adverse effects were noted, suggesting that SM may play a role in better heart recovery post-infarction.
The results were promising; those treated with SM showed a significant decrease in plasma triglyceride levels. This reduction was linked to less absorption of triglycerides and improved heart function.
Despite these findings, no significant adverse effects were noted, suggesting that SM may play a role in better heart recovery post-infarction.
Read More
Most Useful Reviews
9
Excellent for heart
I took this product based on Dr. Karim Ali’s endorsement. It is exceptional for heart health and the additional benefits he mentioned in his episode. I've been using it for a while and decided to purchase it again.
Read More
7.5
Heart product love
This is one of my favourite products for heart health. The scent is lovely, the quality is excellent, and the dosage size is perfect.
Read More
4
Caution advised
2 people found this helpful
Ladies, please pay attention! I bought two packs aiming to use them for a month, but I only managed 16 days. During my routine tests, I discovered significant lethargy in my thyroid gland! After researching glutathione, I realised its potential to cause deficiencies. Though opinions vary, most agree on this, so be careful and consult a doctor before use.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.7
- All Researches
9
We investigated the effects of 2,3-dehydrosilybin, a component of silybum marianum, on heart protection during ischemia and reperfusion injuries in rats. Hearts treated with low doses of this compound experienced significantly reduced damage compared to untreated ones—only about 7.5% of the heart was affected versus over 75% in controls.
This suggests that silybum marianum could effectively support heart health by minimizing injury during heart attacks. Importantly, when specific kinases were inhibited, this protective effect vanished, highlighting the complexity of the mechanisms involved.
This suggests that silybum marianum could effectively support heart health by minimizing injury during heart attacks. Importantly, when specific kinases were inhibited, this protective effect vanished, highlighting the complexity of the mechanisms involved.
Read More
9
Silybum marianum shows heart protection
We examined how silybum marianum, commonly known as milk thistle, impacts the heart during and after a heart attack in pigs.
In the first phase of our study, animals that received milk thistle before a heart attack showed reduced heart damage compared to those who did not.
In the recovery period, those on a continuous milk thistle diet also displayed better heart remodeling and function.
However, there were no significant benefits observed in pigs without heart attacks.
In the first phase of our study, animals that received milk thistle before a heart attack showed reduced heart damage compared to those who did not.
In the recovery period, those on a continuous milk thistle diet also displayed better heart remodeling and function.
However, there were no significant benefits observed in pigs without heart attacks.
Read More
8
We explored the potential benefits of Silybum marianum (SM) on heart health, specifically looking at its effects on cardiac lipotoxicity after a heart attack in pigs. In our study, pigs received either SM or a placebo for ten days.
The results were promising; those treated with SM showed a significant decrease in plasma triglyceride levels. This reduction was linked to less absorption of triglycerides and improved heart function.
Despite these findings, no significant adverse effects were noted, suggesting that SM may play a role in better heart recovery post-infarction.
The results were promising; those treated with SM showed a significant decrease in plasma triglyceride levels. This reduction was linked to less absorption of triglycerides and improved heart function.
Despite these findings, no significant adverse effects were noted, suggesting that SM may play a role in better heart recovery post-infarction.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Excellent for heart
I took this product based on Dr. Karim Ali’s endorsement. It is exceptional for heart health and the additional benefits he mentioned in his episode. I've been using it for a while and decided to purchase it again.
Read More
7.5
Heart product love
This is one of my favourite products for heart health. The scent is lovely, the quality is excellent, and the dosage size is perfect.
Read More
4
Caution advised
2 people found this helpful
Ladies, please pay attention! I bought two packs aiming to use them for a month, but I only managed 16 days. During my routine tests, I discovered significant lethargy in my thyroid gland! After researching glutathione, I realised its potential to cause deficiencies. Though opinions vary, most agree on this, so be careful and consult a doctor before use.
Read More
Frequently Asked Questions
9
Excellent for heart
I took this product based on Dr. Karim Ali’s endorsement. It is exceptional for heart health and the additional benefits he mentioned in his episode. I've been using it for a while and decided to purchase it again.
7.5
Heart product love
This is one of my favourite products for heart health. The scent is lovely, the quality is excellent, and the dosage size is perfect.
4
Caution advised
2 people found this helpful
Ladies, please pay attention! I bought two packs aiming to use them for a month, but I only managed 16 days. During my routine tests, I discovered significant lethargy in my thyroid gland! After researching glutathione, I realised its potential to cause deficiencies. Though opinions vary, most agree on this, so be careful and consult a doctor before use.
9
Silybum marianum shows heart protection
We examined how silybum marianum, commonly known as milk thistle, impacts the heart during and after a heart attack in pigs.
In the first phase of our study, animals that received milk thistle before a heart attack showed reduced heart damage compared to those who did not.
In the recovery period, those on a continuous milk thistle diet also displayed better heart remodeling and function.
However, there were no significant benefits observed in pigs without heart attacks.
In the first phase of our study, animals that received milk thistle before a heart attack showed reduced heart damage compared to those who did not.
In the recovery period, those on a continuous milk thistle diet also displayed better heart remodeling and function.
However, there were no significant benefits observed in pigs without heart attacks.
8
We explored the potential benefits of Silybum marianum (SM) on heart health, specifically looking at its effects on cardiac lipotoxicity after a heart attack in pigs. In our study, pigs received either SM or a placebo for ten days.
The results were promising; those treated with SM showed a significant decrease in plasma triglyceride levels. This reduction was linked to less absorption of triglycerides and improved heart function.
Despite these findings, no significant adverse effects were noted, suggesting that SM may play a role in better heart recovery post-infarction.
The results were promising; those treated with SM showed a significant decrease in plasma triglyceride levels. This reduction was linked to less absorption of triglycerides and improved heart function.
Despite these findings, no significant adverse effects were noted, suggesting that SM may play a role in better heart recovery post-infarction.
9
We investigated the effects of 2,3-dehydrosilybin, a component of silybum marianum, on heart protection during ischemia and reperfusion injuries in rats. Hearts treated with low doses of this compound experienced significantly reduced damage compared to untreated ones—only about 7.5% of the heart was affected versus over 75% in controls.
This suggests that silybum marianum could effectively support heart health by minimizing injury during heart attacks. Importantly, when specific kinases were inhibited, this protective effect vanished, highlighting the complexity of the mechanisms involved.
This suggests that silybum marianum could effectively support heart health by minimizing injury during heart attacks. Importantly, when specific kinases were inhibited, this protective effect vanished, highlighting the complexity of the mechanisms involved.
References
- Vilahur G, Sutelman P, Mendieta G, Ben-Aicha S, Borrell-Pages M, et al. Triglyceride-induced cardiac lipotoxicity is mitigated by Silybum marianum. Atherosclerosis. 2021;324:91. doi:10.1016/j.atherosclerosis.2021.03.014
- Gabrielová E, Bartošíková L, Nečas J, Modrianský M. Cardioprotective effect of 2,3-dehydrosilybin preconditioning in isolated rat heart. Fitoterapia. 2019;132:12. doi:10.1016/j.fitote.2018.10.028
- Vilahur G, Casaní L, Peña E, Crespo J, Juan-Babot O, et al. Silybum marianum provides cardioprotection and limits adverse remodeling post-myocardial infarction by mitigating oxidative stress and reactive fibrosis. Int J Cardiol. 2018;270:28. doi:10.1016/j.ijcard.2018.06.030
